Causes of Rheumatoid Arthritis |
Rheumatoid arthritis is an autoimmune disease with unknown causes. There is currently no known cure or means of preventing rheumatoid arthritis 51. Evidence exists that rheumatoid arthritis may have a genetic component 1. Some people with rheumatoid arthritis have a genetic marker called HLA-DR4 32. The genetic marker may make it more likely that the immune system will attack the body's joint tissues, causing inflammation and pain. It is also possible that certain viruses, bacteria, or environmental contaminants might cause the immune system to malfunction and attack joint tissue.Rheumatoid arthritis is frequently accompanied by Graves’ disease, an auto-immune disease of the thyroid. In fact, many people with endocrine disorders, such as diabetes and hypothyroidism, have some symptoms of rheumatoid arthritis. Individuals with Graves’ disease and Hashimoto's thyroiditis have higher than average occurrences of rheumatoid arthritis; researchers suspect there is a link between the conditions 32. |
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